5.Molecular Basis of Inheritance
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What are the structures called that give an appearance as ‘beads­on­string’ in the chromosomes when viewed under electron microscope?

A

Genes

B

Nucleotides

C

Nucleosomes

D

Base pairs

(AIPMT-2011)

Solution

(c) : Nucleosomes appear as ‘beads­on­string’ in the chromosome when viewed under electron microscope. The beads in ‘beads­on­string’ arrangement are complexes of histones and $DNA$. The bead plus the connecting $DNA$ that leads to the next bead from the nucleosome. Nucleosome is the fundamental unit of organization on which the higher­ order packaging of chromatin is built. The bead of each nucleosome contains eight histone molecules in which two copies each of $H_2A, H_2B, H_3$ and $H_4$ are found.

Standard 12
Biology

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