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According to Hardy-Weinberg principle, allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences. It makes several assumptions which were given below.
$i.$ Random Mating
$ii.$ Sexual Reproduction
$iii.$ Non-overlapping Generations
$iv.$ Occurrence of Natural Selection
$v.$ Small size of population
Identify two assumptions which do not meet for a population to reach Hardy-Weinberg Equilibrium?
$iv$ and $v$
$ii$ and $iv$
$iii,\,iv$ and $v$
$i,\,ii$ and $iii$
Solution
Occurrence of natural selection and small size of population do not meet the criteria for a population to reach Hardy-Weinberg Equilibrium. For Hardy-Weinberg equilibrium to be reached, natural selection should not be occurring. If populations are undergoing natural selection at the locus under consideration, allele frequencies will be continuously changing in a specificdirection and Hardy-Weinberg Equilibrium predicts that allele frequencies will stay constant. It assumes that population size is very large.