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4.Principles of Inheritance and Variation
normal
Based on Lyon’s hypothesis, what will be the number of Barr bodies found in a human female suffering from Down’s syndrome
A
$0$
B
$1$
C
$2$
D
$3$
(AIEEE-2004)
Solution
(b) Down’s syndrome is a chromosomal abnormality in humans and is associated with an extra chromosome $21$ (i.e. chromosomal formula is $45 + xx = 47$),
while one of the two $x$-chromosomes becomes genetically inert and heteropycnotic and forms the Barr body.
Hence human female suffering from Down’s syndrome contains $(2x -1 = 1)$ one Barr body.
Standard 12
Biology