Gujarati
4.Principles of Inheritance and Variation
normal

Based on Lyon’s hypothesis, what will be the number of Barr bodies found in a human female suffering from Down’s syndrome

A

$0$

B

$1$

C

$2$

D

$3$

(AIEEE-2004)

Solution

(b) Down’s syndrome is a chromosomal abnormality in humans and is associated with an extra chromosome $21$ (i.e. chromosomal formula is $45 + xx = 47$),

while one of the two $x$-chromosomes becomes genetically inert and heteropycnotic and forms the Barr body.

Hence human female suffering from Down’s syndrome contains $(2x -1 = 1)$ one Barr body.

Standard 12
Biology

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