Bt toxin kills insect by

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10.Biotechnology and its Application

normal

Bt toxin kills the insect by

Blocking mitochondrial respiration

Blocking transfer of nerve impulse

Creating pores in body surface

Creating pores in mid-gut epithelial cell

Solution

After ingestion by the insect, the protoxin is converted/cleaved into shorter versions of the protein that display the toxic activity. These bind to the mid gut epithelium and create pores that cause cell swelling and lysis. The insect is unable to feed and consequently starves to death.

Standard 12

Biology