Cri­-du-­chat syndrome in humans is caused by the

  • [AIPMT 2006]
  • A

    trisomy of $21^{st}$ chromosome

  • B

    fertilization of an $XX$ egg by a normal $Y$-­bearing sperm

  • C

    loss of half of the short arm of chromosome $5$

  • D

    loss of half of the long arm of chromosome $5$

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