Give differences : Haemophilia and Sickle-cell Anaemia
 

Vedclass pdf generator app on play store
Vedclass iOS app on app store
Haemophilia Sickle-cell Anaemia
$(1)$ It occur due to a defective recessive allele present on the $X$-chromosome. $(1)$ It occurs due to point mutation i.e. a single base pair change leads to a change in amino acid.
$(2)$ The defective allele produce nonfunctional protein which later form a non-functional protein which later form a non-functional cascade of protein involving in blood clotting $(2)$ In this glutamic ($Glu$) acid is replaced by Valine ($Val$) at sixth position of beta globin chain of haemoglobin molecule.
$(3)$ It is a sex-linked recessive disorder. $(3)$ It is an autosomal linked recessive disorder.
$(4)$ More males are affected than females. $(4)$ Both males and females are affected equally.

 

Similar Questions

:Match the columns :

Column $I$
 
Column $II$
 
$(a)$ Sickle cell anaemia  $(x)$ Homogentisic acid
$(b)$ Alkaptonuria $(y)$  Melanin pigmentsare absent
$(c)$ Albinism $(z)$  More amount of phenyl alanine
$(d)$ Phenyl Ketonuria $(w)$  Defective haemoglobin

Sex linked disease is

Sickle cell anaemia is due to

  • [AIPMT 1990]

Given below is a highly simplified representation of the human sex chromosomes from a karyotype. The gene $'a'$ and $'b'$ could be of

If a character is always transmitted directly from a father to all his sons and from their sons to all their sons, then which chromosome carries the gene for the character