Give the historical background of $DNA.$
$DNA$ as an acidic substance present in nucleus was first identified by Friedrich Meischer in $1869 .$ He named it as 'Nuclein'.
Due to technical limitation in isolating such a long polymer intact the elucidation of structure of $DNA$ remained elusive for a very long period of time.
It was only in $1953$ that James Watson and Francis Crick, based on the $X$-ray diffraction data produced by Maurice Wilkins and Rosalind Franklin proposed a very simple but famous Double Helix model for the structure of $DNA$.
One of the hallmarks of their proposition was also based on the observation of Erwin Chargaff that for a double stranded $DNA $ the ratio between Adenine and Thymine and Guanine and cytosine are constant and equals one.
The two strands of $DNA$ are held together by
Describe double helix structure of $DNA$ and how are the sequences of other strand predicted.
In an experiment, $DNA$ is treated with a compound which tends to place itself amongst the stacks of nitrogenous base pairs. As a result of this, the distancebetween two consecutive base increases. from $0.34- 0.44\,nm$ calculate the length of $DNA$ double helix $($ which has $2 \times 10^9\,bP)$ in the presence of saturating amount of this compound.
The two strands of a double helix model of $DNA$ are held together by hydrogen bonds between
..............is common for both $DNA$ and $RNA$ but.............is present only in $DNA$