Removal of which chain results in maturation of proinsulin to insulin?

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10.Biotechnology and its Application

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Removal of which chain results in maturation of proinsulin to insulin?

$D$ chain

$C$ chain

$B$ chain

$A$ chain

Solution

Insulin is synthesized as a pro-hormone and the gene for this protein synthesis is located on chromosome
$11$, and contains an extra stretch called the $C-$peptide.
This $C-$peptide is removed during maturation into insulin.

Standard 12

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Solution

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