Sickle cell anaemia is

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Sickle cell anaemia is caused by a change in a single base pair of DNA. It is an autosomal recessive genetic disease reported from Negroes. In sickle

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Caused by substitution of glutamic acid by valic acid in the $\beta$-globin chain of haemoglobin

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Sickle cell anaemia is caused by a change in a single base pair of DNA. It is an autosomal recessive genetic disease reported from Negroes. In sickle cell haemoglobin the glutamic acid in beta haemoglobin chain is replaced by valine.

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