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4.Principles of Inheritance and Variation
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The most important example of point mutation is found in a disease called
A
Thalassemia
B
Night blindness
C
Down's syndrome
D
Sickle-cell anaemia
Solution
Sickle-cell anaemia is caused due to base replacement leading to replacement of sixth amino acid in the -chain. Glutamic acid is replaced by valine and causes sickle cell anaemia.
Standard 12
Biology
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