What would happen if histones were to be mutated and made rich in acidic amino acids such as aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?
What would happen if histones were to be mutated and made rich in acidic amino acids such as aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in $DNA$ packaging in eukaryotes as $DNA$ is also negatively charged molecule. The packaging of $DNA$ around the nucleosome would not happen. Consequently, the chromatin fibre would not be formed.
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Given below are two statements:
Statement $I$: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid.
Statement $II$: In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome.
In the light of the above statements, choose the correct answer from the options given below:
Given below are two statements:
Statement $I$: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid.
Statement $II$: In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome.
In the light of the above statements, choose the correct answer from the options given below:
- [NEET 2023]