Which of following peptide chain is removed during maturation of proinsulin into insulin?

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10.Biotechnology and its Application

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Which of the following peptide chain is removed during the maturation of proinsulin into insulin?

$A-$chain ( $21$ amino acid)

$B-$chain ( $30$ amino acid)

$C-$chain ( $33$ amino acid)

$A$ and $B$ chain

Solution

Insulin contains two short polypeptide chains, chain $A$ and $B$-chain linked by disulphide bridge. In mammals, insulin is synthesised as prohormone (that needs to be processed to become mature and functional hormone). It contains an extra stretch called-peptide. $C-$peptide is absent in mature insulin and is removed during the maturation into insulin

Standard 12

Biology

Why would lac z gene be fused to coding sequence of chain $A$ and $B$ in plasmids of $E.$coli?

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$A$ : Production of hirudin from transgenic Brassica required use of synthetic gene.

$R $ : Eukaryotic genes have intron sequences that need to be spliced out.

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Define transgenic animals. Explain in detail any four areas where they can be utilised.

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Biotechnology is the modern branch of biology which deals with

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Maximum number of existing transgenicanimals is of

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Which of the following peptide chain is removed during the maturation of proinsulin into insulin?

Solution

Similar Questions

Why would lac z gene be fused to coding sequence of chain $A$ and $B$ in plasmids of $E.$coli?

$A$ : Production of hirudin from transgenic Brassica required use of synthetic gene. $R $ : Eukaryotic genes have intron sequences that need to be spliced out.

Define transgenic animals. Explain in detail any four areas where they can be utilised.

Biotechnology is the modern branch of biology which deals with

Maximum number of existing transgenicanimals is of

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$A$ : Production of hirudin from transgenic Brassica required use of synthetic gene.

$R $ : Eukaryotic genes have intron sequences that need to be spliced out.