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5.Molecular Basis of Inheritance
medium
Which one of the following is not applicableto $RNA$ ?
A
Heterocyclic nitrogenous bases
B
Chargaff’s rule
C
Complementary base pairing
D
$5’ $ phosphoryl and $3’$ hydroxyl ends
(NEET-2015)
Solution
(b) : Chargaff’s rules are applicable only for double stranded $DNA$ molecule. These are not applicable for single stranded $DNA$ or $RNA$ molecules. Chargaff’s rules state that $DNA$ helices contain equal molar ratios of $A$ and $T, G $ and $C$. This is because in a ds $DNA$ molecule, complementary base pairing occurs between $A$ and $T$, and $C$ and $G$ base pairs. This complementary base pairing is not possible in case of single stranded $RNA$ molecule. Thus, Chargaff’s rules are not applicable to $RNA$.
Standard 12
Biology
