Identify the blank spaces $A, B, C, D$ given in the following table and select the correct answer

The product of Monascus purpureus has been commercialised as

$A $ : Statins are product of fermentation activity of yeast.
$R$ : Statins and mevalonate compete for same active site on enzyme involved in cholesterol synthesis.

The bottled juices are clarified by the use ofPectinases

Penicillin was discovered by