Describe in short about $RNA.$
$RNA$ : A nucleotide has three components -a nitrogenous base, a pentose sugar (ribose in case of $RNA$ , and deoxyribose for $DNA$ ), and a phosphate group.
$2'-OH$ group present at every nucleotide in $RNA$ is a reactive group and makes $RNA$ labile and easily degradable. $RNA$ is also now known to be catalytic, hence reactive.
$RNA$ was the first genetic material. There is now enough evidence to suggest that essential life processes (such as metabolism, translation, splicing, etc.), evolved around $RNA$.
$RNA$ used to act as a genetic material as well as a catalyst (there are some important biochemical reactions in living systems that are catalysed by $RNA$ catalysts and not by protein enzymes). But, $RNA$ being a catalyst was reactive and hence unstable.
Therefore, $DNA$ has evolved from $RNA$ with chemical modifications that make it more stable. $DNA$ being double stranded and having complementary strand further resists changes by evolving a process of repair.
The unequivocal proof of $DNA$ as the genetic material came from the studies on a
Which scientist experimentally proved that $DNA$ is the sole genetic material in bacteriophage ?
Who revealed biochemical nature of the transforming principle ? How was it done ?
Transformation experiments using Pneumococcus bacteria led to the hypothesis that
$DNA$ exists in a double-stranded form whereas $RNA $ is mainly a single stranded molecule. What is the likely reason for $DNA$ being double stranded?