19.Chemical Coordination and Integration
medium

One of the following symptoms pertain to Addison’s disease

A

Low plasma $Na^+$, high plasma $K^+$, increased urinary $Na^+$, low blood sugar, vomitting, nausea and diarrhoea

B

High blood sugar, obesity, wasting of limb muscles, fall in plasma $K^+$, high blood $Na^+$, rise in blood volume and high blood pressure

C

Stunted growth, retarded sexual development, mental backwardness

D

Increase of heart beat, rise in blood pressure, nervousness, bulging eyes, warm skin

Solution

Function of adrenal cortex' hormone (mineralocorticoids)
$\rightarrow$ Increase blood levels of $Na^+$ and water
$\rightarrow$ Decrease in blood $K^+$ level
$\rightarrow$ Tubular reabsorption of $Na^+$
$\rightarrow$ Glycogenolysis

A destruction of adrenal cortex by diseases like tuberculosis produces addison disease due to the deficiency
of both glucocorticoids and mineralocorticoids. This condition is known as addison's syndrome and the
consequent symptoms.
Imbalance of $K^+$ leads to vomitting, nausea and diarrhoea.

Standard 11
Biology

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