Select the incorrect statement with regard to | vedclass

Name: PDF Generator App | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(a): Haemophilia is sex&shy;linked disease which is also known as bleeder&rsquo;s disease as the patient will continue to bleed even from a minor cut

Vedclass · Accepted Answer

It is a dominant disease.

Vedclass · Answer

(a): Haemophilia is sex&shy;linked disease which is also known as bleeder&rsquo;s disease as the patient will continue to bleed even from a minor cut since he or she does not possess the natural phenomenon of blood clotting due to absence of antihaemophiliac globulin or factor $VIII$ (haemophilia -$A$) and plasma thromboplastin factor $IX$ (haemophilia-$B$, Christmas disease) essential for it. As a result of continuous bleeding the patient may die of blood loss. It is geneticallydue to the presence ofa recessive sex linked gene $h$, carried by $X$-&shy;chromosome. A female becomes haemophiliac only when both of her $X$-&shy;chromosomes carry the gene $(X^hX^h)$. However, such females generally die before birth because the combination of these two recessive alleles is lethal. A female having only one allele for haemophilia $(XX^h)$ appears normal because the allele for normal blood clotting present on the other X&shy;chromosome is dominant. Such females are known as carriers. In case of males, a single gene for the defect is able to express itself as the $Y$&shy; chromosome is devoid of any corresponding allele $(X^hY)$.

Select the incorrect statement with regard to haemophilia.

Similar Questions

Which of the following is an example of sex-linked disease?

Carrier of genes of colour blindness are present in

In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree.

Which is correct for inheritance of autosome linked recessive gene?

Haemophillic man marries a normal woman. Their offsprings will be