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4.Principles of Inheritance and Variation
normal
The defect sickle-cell anaemia is caused by the ______ of glutamic acid by valine at the $6^{th}$ position of the ______ globin chain of the haemoglobin molecule.
A
Substitution, $\beta$
B
Deletion, $\alpha$
C
Duplication, $\beta$
D
Translocation, $\alpha$
Solution

Substitution of Pyrimidine $\rightleftharpoons$ Purine
Standard 12
Biology