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5.Molecular Basis of Inheritance
normal
Which antibiotic inhibits interaction between $tRNA$ and $mRNA$ during bacterial protein synthesis ?
A
Tetracycline
B
Erythromycin
C
Neomycin
D
Streptomycin
(AIPMT-2006)
Solution
(c) : Neomycin is a broad spectrum antibiotic which was first isolated from a strain of Streptomyces feadiae. It is effective against Gram positive as well as Gram negative bacteria. Its mechanism of action is by selective inhibition of protein synthesis on the $70S$ (prokaryotic) ribosome by inhibiting the interaction of $mRNA$ and $tRNA$ during translation process.
Standard 12
Biology