Can we neglect the quantization of charge ? If yes, then mention the situation ?

Yes, the step size $e$ is however very small because at the macroscopic level. We deal with charges of a few $\mu \mathrm{C}$. At this scale the fact that charge of a body can increases or decrease in units of $e$ is not visible.

The grainy nature of the charge is lost and it appears to be continuous.

This situation can be compared with the geometrical concepts of points and lines.

A dotted line viewed from a distance appears continuous to us but is not continuous in reality.

As many points very close to each other normally give an impression of a continuous line, many small charges taken together appear as a continuous charge distribution.

At the macroscopic level, one deals with charges that are enormous compared to the magnitude of charge $e$.

A charge of magnitude $1 \mu \mathrm{C}$ contains $10^{13}$ times the electronic charge. At this scale, the fact that charge can increase or decrease only in units of $e$ is not very different from saying that charge can take continuous values.

Thus, at the macroscopic level, the quantisation of charge has no practical consequence and can be ignored.

At the microscopic level, where the charges involved are of the order of a few tens or hundreds of $e$, i.e. they can be counted, they appear in discrete lumps and quantisation of charge cannot be ignored.

For more information : Characteristics of electric charge

$(1)$ Electric charge is of two types:

$(i)$ Positive, $(ii)$ Negative

$(2)$ Like charges repel and unlike charges attract.

$(3)$ There is no existance of electric charge without mass.

$(4)$ Magnitude of charge doesn't depend on mass and speed.