In how many ways can a girl and a boy be selected from a group of $15$ boys and $8 $ girls

The number of ways of choosing $10$ objects out of $31$ objects of which $10$ are identical and the remaining $21$ are distinct, is

Number of different words that can be formed from all letters of word $APPLICATION$ such that two vowels never come together is -

Determine the number of $5$ card combinations out of a deck of $52$ cards if there is exactly one ace in each combination.

Let

$S _1=\{( i , j , k ): i , j , k \in\{1,2, \ldots, 10\}\}$

$S _2=\{( i , j ): 1 \leq i < j +2 \leq 10, i , j \in\{1,2, \ldots, 10\}\},$

$S _3=\{( i , j , k , l): 1 \leq i < j < k < l, i , j , k , l \in\{1,2, \ldots ., 10\}\}$

$S _4=\{( i , j , k , l): i , j , k$ and $l$ are distinct elements in $\{1,2, \ldots, 10\}\}$

and  If the total number of elements in the set $S _t$ is $n _z, r =1,2,3,4$, then which of the following statements is (are) TRUE?

$(A)$ $n _1=1000$   $(B)$ $n _2=44$   $(C)$ $n _3=220$   $(D)$ $\frac{ n _4}{12}=420$

In how many ways $5$ speakers $S_1,S_2,S_3,S_4$ and $S_5$ can give speeches one after the other if $S_3$ wants to speak after $S_1$ & $S_2$